Serum Substitutes
Cayman Chemical SR 57227AhydrochlorIde 50mg
A 5-HT3 receptor agonist; selectively binds 5-HT3 receptors (IC50 = 2.8 nM) over 5-HT1A, 5-HT1B, 5-HT1D, 5-HT2, and 5-HT4 receptors (IC50s = >1,000 nM for all); induces contractions in isolated guinea pig ileum at 20 µM; intrastriatal administration induces contralateral turning behavior in mice at 1 UG/animal; reduces immobility time in the forced swim test in rats (ED50 = 7.6 mg/kg); reduces the number of escape failures in a rat model of learned helplessness and the duration of fighting in a mouse model of isolation-induced aggression
Cayman Chemical ANTIBODY SR 4835 5mg
A Cdk12 and Cdk13 inhibitor; binds to Cdk12 and Cdk13 (Kds = 98 and 4.9 nM, respectively); inhibits Cdk12- and Cdk13-dependent phosphorylation of RNA polymerase II in MDA-MB-231 cells (EC50 = 105.5 nM); inhibits the proliferation of MDA-MB-231, MDA-MB-468, Hs 578T, and MDA-MB-436 breast cancer cells (EC50s = 15.5, 22.1, 19.9, and 24.9 nM, respectively); induces the DNA damage response and apoptosis in MDA-MB-231 from 30-90 nM; reduces tumor volume and decreases the number of mice with tumors greater than 1,000 mm3 in a PDX model of breast cancer at 20 mg/kg
ILEX LIFE SCIENCES LLC PAN-Biotech Panexin basic, Serum Replacement with Defined Components (100 ml)
Panexin basic, Serum Replacement with Defined Components. QUANTITY: 100 ml. MANUFACTURED BY: Pan-Biotech (Germany). STORAGE: -20 degrees Celsius. DESCRIPTION: Panexin basic is a fully defined serum replacement for the cultivation of adherent and non-adherent cells under serum-free culture conditions or to significantly reduce the amount of serum in cell culture. It supports the growth of many cell types in an optimum manner without any extra handling compared to serum. COMPOSITION: Contains purified proteins (less than 1 % w/v), lipids, salts, amino acids, trace elements, hormones and only traces of animal-derived components (less than 1 % w/v). It contains no growth factors, undefined hydrolysates or peptones.
Cayman Chemical SR 59230AhydrochlorIde 5mg
A β3-AR antagonist in animal models; less selective for human β-AR subtypes (Kis = 16.4, 61.9, and 122 nM for β1-, β2-, and β3-AR, respectively); blocks MDMA-induced hyperthermia at low and high concentrations with some α1-AR antagonist properties
Biolegend Brilliant Violet 650TM anti-hu
Brilliant Violet 650™ anti-human IFN-γ [B27]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: ICFC; Size: 100 tests
PRO-SOURCE Seal Kit, Replacement, For MSC #20243648
This seal kit provides the necessary components for replacing worn or damaged seals, ensuring the proper functionality and extending the lifespan of compatible equipment. It is engineered to meet the specifications required for a reliable seal.
- Provides essential components for replacement
- Ensures proper sealing and system integrity
- Manufactured for reliable performance
PRO-SOURCE Seal Kit, For MSC #20243572
This seal kit provides a direct replacement for MSC item #20243572. It is designed to ensure proper functionality and extend the lifespan of compatible equipment.
- Ensures proper functionality for compatible equipment
- Extends the lifespan of existing components
- Manufactured in China
MSC PRO-SOURCE Cylinder Replacement
This PRO-SOURCE cylinder is a direct replacement for MSC #20242939. Designed to ensure seamless integration and reliable performance, it offers a practical solution for maintaining equipment.
Cayman Chemical SR 59230AhydrochlorIde 25mg
A β3-AR antagonist in animal models; less selective for human β-AR subtypes (Kis = 16.4, 61.9, and 122 nM for β1-, β2-, and β3-AR, respectively); blocks MDMA-induced hyperthermia at low and high concentrations with some α1-AR antagonist properties
Cayman Chemical SR 59230AhydrochlorIde 10mg
A β3-AR antagonist in animal models; less selective for human β-AR subtypes (Kis = 16.4, 61.9, and 122 nM for β1-, β2-, and β3-AR, respectively); blocks MDMA-induced hyperthermia at low and high concentrations with some α1-AR antagonist properties
Cayman Chemical SR 717lIthIum salt 10mg
A STING agonist (EC50 = 2.1 µM in a reporter assay); selective for STING over a panel of 468 kinases; increases plasma IFN-β and IL-6 levels in mice at 30 mg/kg; increases the intratumor frequency of CD69+CD8+ T cells, reduces tumor growth, and increases survival in a B16/F10 murine melanoma model
Cayman Chemical SR 717lIthIum salt 5mg
A STING agonist (EC50 = 2.1 µM in a reporter assay); selective for STING over a panel of 468 kinases; increases plasma IFN-β and IL-6 levels in mice at 30 mg/kg; increases the intratumor frequency of CD69+CD8+ T cells, reduces tumor growth, and increases survival in a B16/F10 murine melanoma model
Biolegend Brilliant Violet 650TM anti-hu
Brilliant Violet 650™ anti-human IFN-γ [B27]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: ICFC; Size: 25 tests
ILEX LIFE SCIENCES LLC PAN-Biotech Panexin CD, Serum Replacement with Chemically-Defined Components (500 ml)
Panexin CD: Serum Replacement with Chemically-Defined Components. QUANTITY: 500 ml. MANUFACTURED BY: Pan-Biotech (Germany). STORAGE: -20 degrees Celsius. DESCRIPTION: PAN-Biotech Panexin CD is a chemically defined, xeno-free serum replacement for the cultivation of adherent and non-adherent cells under serum-free culture conditions or to significantly reduce the amount of serum in cell culture. It supports the growth of many cell types in an optimum manner without any extra handling compared to serum. Panexin CD is animal-free and contains recombinant proteins, lipids, salts, amino acids, trace elements, hormones and a 3-dimensional substrate release system in an optimized formulation. It contains no growth factors, undefined hydrolysates or peptones. Compared to other serum replacements, it contains only chemically defined components. Due to its very defined character, lot testing is not necessary allowing for high reproducibility and simplified downstream processing.